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Calendar
Science News
Links
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Please click on the day
to view the daily assignment
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January |
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28
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29
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30
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31 |
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February |
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1
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4
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5
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6
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7
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8
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11 Spring Term Drop/Add
1) Course Syllabus
2) Review: Aqueous Solutions, Buffers
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12 Spring Term Drop/Add
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13 Spring Term Drop/Add
1) Intro to Molecular Modeling
2) Protein Structure: amino acids & peptide bonds, 1o - 2o structure
| Lab1: Modeling |
| Prep Buffers |
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14 Spring Term Drop/Add
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15 Spring Term Drop/Add
1) Review: Among other things basic thermodynamics and IF
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18 Quiz 1
1) Molecular Modeling
2) Protein Structure:secondary, tertiary, quaternary protein structure, motifs
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19
Last Day to turn in Add/Drop form
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20
1) Molecular Modeling
2) Protein Structure:secondary, tertiary, quaternary protein structure, motifs
| Lab2: Intro to TOP |
| Enzyme Kinetics - review |
| TOP Assay |
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21
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22
Work on Activity Assays
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25 Quiz 2
1) Molecular Modeling
2) Protein Structure:secondary, tertiary, quaternary protein structure, motifs
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26
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27
Homology Modeling and Structure Prediction
| Lab3: Finish Assays |
| Begin mutant assays |
| Assign - calc kcat/Km |
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28
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29
Homology Modeling and Structure Prediction
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March |
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Fri |
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3
Methods I - X-ray crystallography, NMR
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4
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5
Protein Folding: In vitro part 1
Science paper - intro folding diseases -------- nature review on folding
| Lab4: Presentation of kinetic data |
| Produce homolgy model of ratTOP |
| Discuss prep of TOP for denaturation |
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6
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7
Protein Folding: In vitro part 1
Science paper - intro folding diseases -------- nature review on folding
Protein Folding: Methods II FTIR, HD exchange. CD |
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10
Protein Folding: Methods II CD, HD exchange. fluorescence
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11
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12
Protein Folding: Methods II CD, HD exchange. fluorescence
Lab5: Intro to protein fluorescence |
13
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14
Exam I
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17 Easter Recess
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18 Easter Recess
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19 Easter Recess
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20 Easter Recess
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21 Easter Recess
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24 Easter Recess
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25
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26
Protein Folding: Chaperones/Fail safes
Lab6: Unfolding of TOP in GuHCl
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27
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28
Protein Folding: Chaperones/Fail safes
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31
Protein Folding: Research article
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April |
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May |
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